ARTICANZ - Beta (ver 0.9)
Annotated Registry of Trials in Cancer, Australia and New Zealand Ed.
- Results - catype/medical-oncology/breast/metastatic/triple-negative/first-line
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ARTICANZ provides informational content about cancer drug trials in Australia/NZ that is updated weekly but may not be completely accurate, and should not replace medical advice from qualified healthcare professionals. The platform is intended to be useful, providing information "as is" without warranties. Non-medical users must always consult healthcare providers for all clinical decisions.
Search results
Breast / Breast - Metastatic / Triple negative / First line
4
trial(s) found.
NCT06926868
Advanced
Phase 2 / Phase 3
Not yet recruiting
A Randomized, Open-label, Inferentially Seamless Phase 2/3 Study of Izalontamab Brengitecan (BMS-986507) Versus Treatment of Physician's Choice in Patients With Previously
Untreated
, Locally Advanced, Recurrent Inoperable,or Metastatic
Triple-negative
Breast Cancer (
TNBC
)or ER-low, HER2-negative BC Who Are Ineligible for Anti-PD1/PD-L1 Treatment (
CA244-0008
)
bispecific EGFR/ERBB3 antibody
Breast cancer
VIC
3000 - Melbourne - Peter MacCallum Cancer Centre
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital
QLD
4032 - Chermside - The Prince Charles Hospital
WA
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital
NCT05382299
Advanced
Phase 3
Recruiting
A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan Versus Treatment of Physician's Choice in Patients With Previously
Untreated
, Locally Advanced, Inoperable or Metastatic
Triple-Negative
Breast Cancer Whose Tumors Do Not Express PD-L1 or in Patients Previously Treated With Anti-PD-(L)1 Agents in the Early Setting Whose Tumors Do Express PD-L1 (
ASCENT-03
)
anti-Trop2 antibody-drug conjugate
Triple-negative breast cancer
NSW
2217 - Kogarah - St George Hospital
2060 - North Sydney - Mater Hospital (WITHDRAWN)
2065 - St Leonards - GenesisCare North Shore Private Hospital (WITHDRAWN)
2640 - Albury - Border Medical Oncology Research Unit (WITHDRAWN)
VIC
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3168 - Clayton - Monash Medical Centre
QLD
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
4102 - Woolloongabba - Princess Alexandra Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
TAS
7000 - Hobart - ICON Cancer Care Hobart (WITHDRAWN)
NCT05852691
Advanced
Phase 2
Active not recruiting
A Phase II, Multicenter, Randomized, Double-Blind Study of Tobemstomig/RO7247669 Combined With Nab-Paclitaxel Compared With Pembrolizumab Combined With Nab-Paclitaxel in Participants With Previously
Untreated
, PD-L1-Positive, Locally-Advanced Unresectable or Metastatic
Triple-Negative
Breast Cancer (
CO44194
)
anti-PD-1 monoclonal antibody
bispecific PD-1/LAG3 antibody
taxane
Breast cancer
VIC
3021 - St Albans - Western Health - Sunshine Hospital
NCT05382286
Advanced
Phase 3
Active not recruiting
A Randomized, Open-label, Phase 3 Study of Sacituzumab Govitecan and Pembrolizumab Versus Treatment of Physician's Choice and Pembrolizumab in Patients With Previously
Untreated
, Locally Advanced Inoperable or Metastatic
Triple-Negative
Breast Cancer, Whose Tumors Express PD-L1 (
ASCENT-04
)
anti-PD-1 monoclonal antibody
anti-Trop2 antibody-drug conjugate
Triple-negative breast cancer
NSW
2060 - North Sydney - Mater Hospital
2065 - St Leonards - GenesisCare North Shore Private Hospital
2217 - Kogarah - St George Hospital
2640 - Albury - Border Medical Oncology Research Unit
VIC
3053 - Parkville - The Royal Women's Hospital and Institute of Maternal and Child Health
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre
3168 - Clayton - Monash Medical Centre
QLD
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre
4102 - Woolloongabba - Princess Alexandra Hospital
SA
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre
WA
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre
TAS
7000 - Hobart - ICON Cancer Care Hobart
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Recruitment Status
Active not recruiting (2)
Not yet recruiting (1)
Recruiting (1)
Recruitment Country and State
VIC (4)
QLD (3)
WA (3)
NSW (2)
SA (2)
TAS (1)
Phase
Phase 2 (1)
Phase 2 / Phase 3 (1)
Phase 3 (2)
Trial Type
Advanced (4)
Cancer Therapy Class
Trop2
50%
PD-1
50%
PD-1/PD-L1
50%
EGFR
25%
ERBB3
25%
LAG3
25%
Facility
3084 - Heidelberg - Austin Hospital Olivia Newton-John Cancer Centre (3)
2060 - North Sydney - Mater Hospital (2)
2065 - St Leonards - GenesisCare North Shore Private Hospital (2)
2217 - Kogarah - St George Hospital (2)
2640 - Albury - Border Medical Oncology Research Unit (2)
3168 - Clayton - Monash Medical Centre (2)
4101 - South Brisbane - Mater Hospital Brisbane / ICON Cancer Centre (2)
4102 - Woolloongabba - Princess Alexandra Hospital (2)
5000 - Adelaide - Royal Adelaide Hospital - Adelaide Cancer Centre (2)
6009 - Nedlands - Sir Charles Gairdner Hospital - WA Cancer Centre (2)
7000 - Hobart - ICON Cancer Care Hobart (2)
3000 - Melbourne - Peter MacCallum Cancer Centre (1)
3350 - Ballarat - Grampians Health Service's Ballarat Base Hospital (1)
4032 - Chermside - The Prince Charles Hospital (1)
6008 - Subiaco - Bendat Family Comprehensive Cancer Centre - St John of God Subiaco Hospital (1)
3021 - St Albans - Western Health - Sunshine Hospital (1)
3053 - Parkville - The Royal Women's Hospital and Institute of Maternal and Child Health (1)
Cancer Type
Breast cancer
Cancer
Solid tumour
Breast adenocarcinoma
Triple-negative breast cancer
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